Coronavirus Outbreak

[happy_tiger]

I don't know about Coronavirus but I think am going to get the 4Pines virus this afternoon
And I may get it more than once

Good drop is it CT

 

[jirskyr]

I can give you some perspective. Currently I am working with an RSV vaccine - RSV is a common source of lung infection (viral), it kills about 500 kids and 14K adults annually in the US (not all countries keep good epidemiological data). Mortality rate is around 1% depending on age group and risk factors.

Almost everyone in the Western world is exposed to RSV during their lives, whether or not they actually have a serious illness in response. The elderly are the highest risk, very similar profile to flu, with annual seasons.

There currently is no marketed vaccine for RSV, this is just research.

Now - I bet not a single one of you have ever heard of RSV.

 

[Tim Sheens]

Coronavirus is obviously a big issue because it’s a new virus without a vaccine at the moment but to put it in perspective there have been less than 2800 deaths worldwide compared to influenza which has an average annual death toll of 650000. Most people don’t spend too much time worrying about the ‘flu’. Yes coronavirus is something to be careful about but people need to keep it in perspective.

Sounds like the Trump, who is a convicted Rapist and Felon perspective and sure, plenty of people die from flu annually, but this disease is at least 10 fold more fatal and likely some 20 times more than the average flu.

The fatality rate seems greater than the Spanish flu which was devastating a century or so ago, which it quite well could soon be, just at this stage it has been limited to one main country and only now showing outbreaks elsewhere.

On tele in the States on Wednesday 240 infants died off the common flu this winter alone .. perspectives has to be applied here . Unfortunately the socialists bed wetters are out in force and stirring the pot and the financial markets are responding !

That is an utterly ridiculous ultimate sentence and as for your first sentence, have you considered the likelihood of those numbers, as with all other health related death numbers in that country, being directly associated with the lack of healthcare coverage?

Everyone with a reasonable knowledge has known throughout their lives that the flu is a killer of the vulnerable and the numbers are huge. The perspective is the mortality rate, which is many, many times lower. People and countries don't change their travel arrangements, shut down regions, schools and factoriesfor the flu because of the negligible risk.

 

[jirskyr]

As for the Spanish flu, it was 100 years ago.

Yeah what a stupid argument, spanish flu of 100 years ago. How about the plague, that was pretty destructive too.

Good luck with any infection, cancer or autoimmune disorder prior to WWI.

As with all pandemics, the community needs to be self-aware and seek medical assistance if they develop symptoms.

There is a huge political football with closing borders etc, however, and it doesn't help at all that anti-China sentiment was already at a pretty high rate globally, based on political manoeuvring, before covid-19 was even a concern.

But there should be no surprise of periodic social health pandemics originating out of countries with massive populations and highly inconsistent levels of medical care, income, living standards and food industry governance.

Lastly, it really makes me wonder about the setup in China, with their sometimes iron-grip on the people and "supposed" communism (in name only), then some national crisis kicks off and the govt proves to be highly ineffective. All that effort to control the population and it all goes to pot on the back of a virus, their systems and strategies ineffective.

 

[LeichhardtTiger]

So if I read this correctly back in 2016 the WORLD BANK set up this financing model (Pandemic Emergency Financing Facility PEF) where it obtained access to $500million to be used if a Global Pandemic emerged within a specific time frame and due to a specifically identified virus, and criteria. In otherwords, an insurance policy which would mature once the set criteria were met.

Apparently, we are approaching the maturity date for this current "insurance policy"

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5594412/

The key paragraph summary is here:

The PEF consists essentially of two financial mechanisms, known as “windows” (fig 2​2).). The first is the “insurance window,” which provides cover of up to $500m for infrequent, severe health pandemics. In an outbreak, part of the money it holds is paid out as long as the following criteria are met15: a country must be affected by a specific kind of pathogen, including orthomyxoviridae (eg, new influenza virus A, B, and C), coronaviridae (eg, severe acute respiratory syndrome, Middle East respiratory syndrome), filoviridae (eg, Ebola, Marburg), and other zoonotic diseases (eg, Crimean Congo, Rift Valley, and Lassa). Moreover, the size of an outbreak, measured in number of cases or of deaths, must be considerable (eg, 2000 confirmed cases worldwide for influenza), outbreak growth must be fast (eg, an increase of confirmed cases from 2000 to 5000 within a month), and spread of the outbreak must be broad (eg, two or more countries must be affected).


Welcome to the New World Order folks. Have we been pranked?

 

[happy_tiger]

I can give you some perspective. Currently I am working with an RSV vaccine - RSV is a common source of lung infection (viral), it kills about 500 kids and 14K adults annually in the US (not all countries keep good epidemiological data). Mortality rate is around 1% depending on age group and risk factors.

Almost everyone in the Western world is exposed to RSV during their lives, whether or not they actually have a serious illness in response. The elderly are the highest risk, very similar profile to flu, with annual seasons.

There currently is no marketed vaccine for RSV, this is just research.

Now - I bet not a single one of you have ever heard of RSV.

Isn't their something a pregnant woman can take to prevent this or prevent it being so virulent

 

[Snake]

So if I read this correctly back in 2016 the WORLD BANK set up this financing model (Pandemic Emergency Financing Facility PEF) where it obtained access to $500million to be used if a Global Pandemic emerged within a specific time frame and due to a specifically identified virus, and criteria. In otherwords, an insurance policy which would mature once the set criteria were met.

Apparently, we are approaching the maturity date for this current "insurance policy"

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5594412/

The key paragraph summary is here:

The PEF consists essentially of two financial mechanisms, known as “windows” (fig 2​2).). The first is the “insurance window,” which provides cover of up to $500m for infrequent, severe health pandemics. In an outbreak, part of the money it holds is paid out as long as the following criteria are met15: a country must be affected by a specific kind of pathogen, including orthomyxoviridae (eg, new influenza virus A, B, and C), coronaviridae (eg, severe acute respiratory syndrome, Middle East respiratory syndrome), filoviridae (eg, Ebola, Marburg), and other zoonotic diseases (eg, Crimean Congo, Rift Valley, and Lassa). Moreover, the size of an outbreak, measured in number of cases or of deaths, must be considerable (eg, 2000 confirmed cases worldwide for influenza), outbreak growth must be fast (eg, an increase of confirmed cases from 2000 to 5000 within a month), and spread of the outbreak must be broad (eg, two or more countries must be affected).


Welcome to the New World Order folks. Have we been pranked?

Yes and put climate change on that agenda as well ! we are being pranked ..beautiful autumn day in Sydney .. no climate change today maybe tomorrow!

 

[Yossarian]

$500m? Lol! The World Bank deals in trillions.

 

[TheDaBoss]

I have a video relating to it...can't upload for some reason...says something about privledge

 

[jirskyr]

I can give you some perspective. Currently I am working with an RSV vaccine - RSV is a common source of lung infection (viral), it kills about 500 kids and 14K adults annually in the US (not all countries keep good epidemiological data). Mortality rate is around 1% depending on age group and risk factors.

Almost everyone in the Western world is exposed to RSV during their lives, whether or not they actually have a serious illness in response. The elderly are the highest risk, very similar profile to flu, with annual seasons.

There currently is no marketed vaccine for RSV, this is just research.

Now - I bet not a single one of you have ever heard of RSV.

Isn't their something a pregnant woman can take to prevent this or prevent it being so virulent

Not yet for RSV, but it is being worked on. You can't stop it being "virulent", because virulence is based on mutations and host susceptibility. But you can develop better and better vaccines, and yes hopefully give them to pregnant women to infer early immunity to the children.

Researching in pregnant mothers and successfully getting vaccines to pass over the placenta is very difficult; for RSV they've been working on it for 60+ years.

Major problem with viruses like flu is how regularly they mutate, so you are always chasing down new immunity, and probably always will be, until we develop nanomachines that can just do the work via software.

 

[Yossarian]

Sounds like you're doing some interesting and important work jirskyr

 

[happy_tiger]

I can give you some perspective. Currently I am working with an RSV vaccine - RSV is a common source of lung infection (viral), it kills about 500 kids and 14K adults annually in the US (not all countries keep good epidemiological data). Mortality rate is around 1% depending on age group and risk factors.

Almost everyone in the Western world is exposed to RSV during their lives, whether or not they actually have a serious illness in response. The elderly are the highest risk, very similar profile to flu, with annual seasons.

There currently is no marketed vaccine for RSV, this is just research.

Now - I bet not a single one of you have ever heard of RSV.

Isn't their something a pregnant woman can take to prevent this or prevent it being so virulent

Not yet for RSV, but it is being worked on. You can't stop it being "virulent", because virulence is based on mutations and host susceptibility. But you can develop better and better vaccines, and yes hopefully give them to pregnant women to infer early immunity to the children.

Researching in pregnant mothers and successfully getting vaccines to pass over the placenta is very difficult; for RSV they've been working on it for 60+ years.

Major problem with viruses like flu is how regularly they mutate, so you are always chasing down new immunity, and probably always will be, until we develop nanomachines that can just do the work via software.

I know Wiki isn't the be all and end all ..but what is the Palivizumab med

I read something a while ago about it couldn't remember the name of it

 

[Cairnstigers]

I don't know about Coronavirus but I think am going to get the 4Pines virus this afternoon
And I may get it more than once

Good drop is it CT

Yea mate
Like my pale ale

 

[Snake]

I can give you some perspective. Currently I am working with an RSV vaccine - RSV is a common source of lung infection (viral), it kills about 500 kids and 14K adults annually in the US (not all countries keep good epidemiological data). Mortality rate is around 1% depending on age group and risk factors.

Almost everyone in the Western world is exposed to RSV during their lives, whether or not they actually have a serious illness in response. The elderly are the highest risk, very similar profile to flu, with annual seasons.

There currently is no marketed vaccine for RSV, this is just research.

Now - I bet not a single one of you have ever heard of RSV.

Isn't their something a pregnant woman can take to prevent this or prevent it being so virulent

Not yet for RSV, but it is being worked on. You can't stop it being "virulent", because virulence is based on mutations and host susceptibility. But you can develop better and better vaccines, and yes hopefully give them to pregnant women to infer early immunity to the children.

Researching in pregnant mothers and successfully getting vaccines to pass over the placenta is very difficult; for RSV they've been working on it for 60+ years.

Major problem with viruses like flu is how regularly they mutate, so you are always chasing down new immunity, and probably always will be, until we develop nanomachines that can just do the work via software.

Cool job pal ... be careful handling those ?..

 

[happy_tiger]

http://www.msn.com/en-au/news/australia/australia-announces-iran-travel-ban-amid-covid-19-coronavirus-outbreak/ar-BB10y78a?li=AAgfYrC&ocid=ASUDHP

 

[TillLindemann]

http://www.msn.com/en-au/news/australia/australia-announces-iran-travel-ban-amid-covid-19-coronavirus-outbreak/ar-BB10y78a?li=AAgfYrC&ocid=ASUDHP

Need to do the same for South Korea and Italy too.

 

[Moh]

Meant to be flying to Japan on Monday four a couple of weeks.

Announced yesterday they've shut down nearly all the tourist hot spots, few of which we were planning on visiting. Trip a bit pointless now.

Been weeks of should we/shouldn't we.... but now our hands are forced.

Leave all booked in, colleagues farewelled Friday arvo... be a nice surprise to see me on Monday.

 

[jirskyr]

I can give you some perspective. Currently I am working with an RSV vaccine - RSV is a common source of lung infection (viral), it kills about 500 kids and 14K adults annually in the US (not all countries keep good epidemiological data). Mortality rate is around 1% depending on age group and risk factors.

Almost everyone in the Western world is exposed to RSV during their lives, whether or not they actually have a serious illness in response. The elderly are the highest risk, very similar profile to flu, with annual seasons.

There currently is no marketed vaccine for RSV, this is just research.

Now - I bet not a single one of you have ever heard of RSV.

Isn't their something a pregnant woman can take to prevent this or prevent it being so virulent

Not yet for RSV, but it is being worked on. You can't stop it being "virulent", because virulence is based on mutations and host susceptibility. But you can develop better and better vaccines, and yes hopefully give them to pregnant women to infer early immunity to the children.

Researching in pregnant mothers and successfully getting vaccines to pass over the placenta is very difficult; for RSV they've been working on it for 60+ years.

Major problem with viruses like flu is how regularly they mutate, so you are always chasing down new immunity, and probably always will be, until we develop nanomachines that can just do the work via software.


Cool job pal ... be careful handling those ?..

Oh, it's not like that, I'm not in a lab, it's more project management. Also we are dealing with a vaccine, so no bugs - we'll measure the number of, or lack of, respiratory conditions at the end of the study.

 

[jirskyr]

Sounds like you're doing some interesting and important work jirskyr

Interesting sometimes, yes, important... ultimately all drug research is important, if you can get it to work. The reality of it is a lot of paperwork, emails, big spending and slow progress. So you can look down the line and hope the drug works, and it can help people, but day-to-day its about meeting timelines and sticking to budgets.

 

[Dyloh]

I never watch the news so I'm not exactly caught up with what's going on. What's the story with how covid-19 originated? Thought it was a bit suspect that there's 1 biochemical research lab in all of China and it's in Wuhan.....